Tom Brevoort, Senior Vice President and Executive Editor at Marvel, has this to say:
"Point One is a massive one-shot of 64 all-new pages of story by the top creators in the business, setting the stage for the biggest stories coming in 2012. It is the starting point to what’s in store for the world’s most iconic characters and startling events. Point One serves as the launch pad for dynamic new series – including one that spins directly out of the smash hit Uncanny X-Force’s ‘Dark Angel Saga’, and a shocking teaser that will have everyone talking. See how all it comes together in one gigantic epic!”
Here's the teaser for the David Lapham/Roberto De La Torre chapter of Point One. That certainly looks like Crossbones, but is this foreground woman Superia or somebody else? Either way, it certainly looks like some kind of Hydra action.